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Niclosamide-loaded nanoparticles disrupt Candida biofilms and protect mice from mucosal candidiasis
Candida albicans biofilms are a complex multilayer community of cells that are resistant to almost all classes of antifungal drugs. The bottommost layers of biofilms experience nutrient limitation where C. albicans cells are required to respire. We previously reported that a protein Ndu1 is essentia...
Autores principales: | Sutar, Yogesh, Nabeela, Sunna, Singh, Shakti, Alqarihi, Abdullah, Solis, Norma, Ghebremariam, Teklegiorgis, Filler, Scott, Ibrahim, Ashraf S., Date, Abhijit, Uppuluri, Priya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385045/ https://www.ncbi.nlm.nih.gov/pubmed/35976859 http://dx.doi.org/10.1371/journal.pbio.3001762 |
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