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Modeling the change in European and US COVID-19 death rates

Motivated by several possible differences in Covid-19 virus strains, age demographics, and face mask wearing between continents and countries, we focussed on changes in Covid death rates in 2020. We have extended our Covid-19 multicompartment model (Khan et al., 2020) to fit cumulative case and deat...

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Autores principales: Khan, Zeina S., Van Bussel, Frank, Hussain, Fazle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385065/
https://www.ncbi.nlm.nih.gov/pubmed/35976910
http://dx.doi.org/10.1371/journal.pone.0268332
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author Khan, Zeina S.
Van Bussel, Frank
Hussain, Fazle
author_facet Khan, Zeina S.
Van Bussel, Frank
Hussain, Fazle
author_sort Khan, Zeina S.
collection PubMed
description Motivated by several possible differences in Covid-19 virus strains, age demographics, and face mask wearing between continents and countries, we focussed on changes in Covid death rates in 2020. We have extended our Covid-19 multicompartment model (Khan et al., 2020) to fit cumulative case and death data for 49 European countries and 52 US states and territories during the recent pandemic, and found that the case mortality rate had decreased by at least 80% in most of the US and at least 90% in most of Europe. We found that death rate decreases do not have strong correlations to other model parameters (such as contact rate) or other standard state/national metrics such as population density, GDP, and median age. Almost all the decreases occurred between mid-April and mid-June 2020, which corresponds to the time when many state and national lockdowns were relaxed resulting in surges of new cases. We examine here several plausible causes for this drop—improvements in treatment, face mask wearing, new virus strains, testing, potentially changing demographics of infected patients, and changes in data collection and reporting—but none of their effects are as significant as the death rate changes suggest. In conclusion, this work shows that a two death rate model is effective in quantifying the reported drop in death rates.
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spelling pubmed-93850652022-08-18 Modeling the change in European and US COVID-19 death rates Khan, Zeina S. Van Bussel, Frank Hussain, Fazle PLoS One Research Article Motivated by several possible differences in Covid-19 virus strains, age demographics, and face mask wearing between continents and countries, we focussed on changes in Covid death rates in 2020. We have extended our Covid-19 multicompartment model (Khan et al., 2020) to fit cumulative case and death data for 49 European countries and 52 US states and territories during the recent pandemic, and found that the case mortality rate had decreased by at least 80% in most of the US and at least 90% in most of Europe. We found that death rate decreases do not have strong correlations to other model parameters (such as contact rate) or other standard state/national metrics such as population density, GDP, and median age. Almost all the decreases occurred between mid-April and mid-June 2020, which corresponds to the time when many state and national lockdowns were relaxed resulting in surges of new cases. We examine here several plausible causes for this drop—improvements in treatment, face mask wearing, new virus strains, testing, potentially changing demographics of infected patients, and changes in data collection and reporting—but none of their effects are as significant as the death rate changes suggest. In conclusion, this work shows that a two death rate model is effective in quantifying the reported drop in death rates. Public Library of Science 2022-08-17 /pmc/articles/PMC9385065/ /pubmed/35976910 http://dx.doi.org/10.1371/journal.pone.0268332 Text en © 2022 Khan et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Khan, Zeina S.
Van Bussel, Frank
Hussain, Fazle
Modeling the change in European and US COVID-19 death rates
title Modeling the change in European and US COVID-19 death rates
title_full Modeling the change in European and US COVID-19 death rates
title_fullStr Modeling the change in European and US COVID-19 death rates
title_full_unstemmed Modeling the change in European and US COVID-19 death rates
title_short Modeling the change in European and US COVID-19 death rates
title_sort modeling the change in european and us covid-19 death rates
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385065/
https://www.ncbi.nlm.nih.gov/pubmed/35976910
http://dx.doi.org/10.1371/journal.pone.0268332
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