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An epidermal electronic system for physiological information acquisition, processing, and storage with an integrated flash memory array

Epidermal electronic systems that simultaneously provide physiological information acquisition, processing, and storage are in high demand for health care/clinical applications. However, these system-level demonstrations using flexible devices are still challenging because of obstacles in device per...

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Detalles Bibliográficos
Autores principales: Xiang, Li, Wang, Yuru, Xia, Fan, Liu, Fang, He, Daliang, Long, Guanhua, Zeng, Xiangwen, Liang, Xuelei, Jin, Chuanhong, Wang, Yuwei, Pan, Anlian, Peng, Lian-Mao, Hu, Youfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385141/
https://www.ncbi.nlm.nih.gov/pubmed/35977018
http://dx.doi.org/10.1126/sciadv.abp8075
Descripción
Sumario:Epidermal electronic systems that simultaneously provide physiological information acquisition, processing, and storage are in high demand for health care/clinical applications. However, these system-level demonstrations using flexible devices are still challenging because of obstacles in device performance, functional module construction, or integration scale. Here, on the basis of carbon nanotubes, we present an epidermal system that incorporates flexible sensors, sensor interface circuits, and an integrated flash memory array to collect physiological information from the human body surface; amplify weak biosignals by high-performance differential amplifiers (voltage gain of 27 decibels, common-mode rejection ratio of >43 decibels, and gain bandwidth product of >22 kilohertz); and store the processed information in the memory array with performance on par with industrial standards (retention time of 10(8) seconds, program/erase voltages of ±2 volts, and endurance of 10(6) cycles). The results shed light on the great application potential of epidermal electronic systems in personalized diagnostic and physiological monitoring.