Cargando…

An epidermal electronic system for physiological information acquisition, processing, and storage with an integrated flash memory array

Epidermal electronic systems that simultaneously provide physiological information acquisition, processing, and storage are in high demand for health care/clinical applications. However, these system-level demonstrations using flexible devices are still challenging because of obstacles in device per...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiang, Li, Wang, Yuru, Xia, Fan, Liu, Fang, He, Daliang, Long, Guanhua, Zeng, Xiangwen, Liang, Xuelei, Jin, Chuanhong, Wang, Yuwei, Pan, Anlian, Peng, Lian-Mao, Hu, Youfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385141/
https://www.ncbi.nlm.nih.gov/pubmed/35977018
http://dx.doi.org/10.1126/sciadv.abp8075
_version_ 1784769532905127936
author Xiang, Li
Wang, Yuru
Xia, Fan
Liu, Fang
He, Daliang
Long, Guanhua
Zeng, Xiangwen
Liang, Xuelei
Jin, Chuanhong
Wang, Yuwei
Pan, Anlian
Peng, Lian-Mao
Hu, Youfan
author_facet Xiang, Li
Wang, Yuru
Xia, Fan
Liu, Fang
He, Daliang
Long, Guanhua
Zeng, Xiangwen
Liang, Xuelei
Jin, Chuanhong
Wang, Yuwei
Pan, Anlian
Peng, Lian-Mao
Hu, Youfan
author_sort Xiang, Li
collection PubMed
description Epidermal electronic systems that simultaneously provide physiological information acquisition, processing, and storage are in high demand for health care/clinical applications. However, these system-level demonstrations using flexible devices are still challenging because of obstacles in device performance, functional module construction, or integration scale. Here, on the basis of carbon nanotubes, we present an epidermal system that incorporates flexible sensors, sensor interface circuits, and an integrated flash memory array to collect physiological information from the human body surface; amplify weak biosignals by high-performance differential amplifiers (voltage gain of 27 decibels, common-mode rejection ratio of >43 decibels, and gain bandwidth product of >22 kilohertz); and store the processed information in the memory array with performance on par with industrial standards (retention time of 10(8) seconds, program/erase voltages of ±2 volts, and endurance of 10(6) cycles). The results shed light on the great application potential of epidermal electronic systems in personalized diagnostic and physiological monitoring.
format Online
Article
Text
id pubmed-9385141
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher American Association for the Advancement of Science
record_format MEDLINE/PubMed
spelling pubmed-93851412022-08-26 An epidermal electronic system for physiological information acquisition, processing, and storage with an integrated flash memory array Xiang, Li Wang, Yuru Xia, Fan Liu, Fang He, Daliang Long, Guanhua Zeng, Xiangwen Liang, Xuelei Jin, Chuanhong Wang, Yuwei Pan, Anlian Peng, Lian-Mao Hu, Youfan Sci Adv Physical and Materials Sciences Epidermal electronic systems that simultaneously provide physiological information acquisition, processing, and storage are in high demand for health care/clinical applications. However, these system-level demonstrations using flexible devices are still challenging because of obstacles in device performance, functional module construction, or integration scale. Here, on the basis of carbon nanotubes, we present an epidermal system that incorporates flexible sensors, sensor interface circuits, and an integrated flash memory array to collect physiological information from the human body surface; amplify weak biosignals by high-performance differential amplifiers (voltage gain of 27 decibels, common-mode rejection ratio of >43 decibels, and gain bandwidth product of >22 kilohertz); and store the processed information in the memory array with performance on par with industrial standards (retention time of 10(8) seconds, program/erase voltages of ±2 volts, and endurance of 10(6) cycles). The results shed light on the great application potential of epidermal electronic systems in personalized diagnostic and physiological monitoring. American Association for the Advancement of Science 2022-08-17 /pmc/articles/PMC9385141/ /pubmed/35977018 http://dx.doi.org/10.1126/sciadv.abp8075 Text en Copyright © 2022 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC). https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license (https://creativecommons.org/licenses/by-nc/4.0/) , which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited.
spellingShingle Physical and Materials Sciences
Xiang, Li
Wang, Yuru
Xia, Fan
Liu, Fang
He, Daliang
Long, Guanhua
Zeng, Xiangwen
Liang, Xuelei
Jin, Chuanhong
Wang, Yuwei
Pan, Anlian
Peng, Lian-Mao
Hu, Youfan
An epidermal electronic system for physiological information acquisition, processing, and storage with an integrated flash memory array
title An epidermal electronic system for physiological information acquisition, processing, and storage with an integrated flash memory array
title_full An epidermal electronic system for physiological information acquisition, processing, and storage with an integrated flash memory array
title_fullStr An epidermal electronic system for physiological information acquisition, processing, and storage with an integrated flash memory array
title_full_unstemmed An epidermal electronic system for physiological information acquisition, processing, and storage with an integrated flash memory array
title_short An epidermal electronic system for physiological information acquisition, processing, and storage with an integrated flash memory array
title_sort epidermal electronic system for physiological information acquisition, processing, and storage with an integrated flash memory array
topic Physical and Materials Sciences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385141/
https://www.ncbi.nlm.nih.gov/pubmed/35977018
http://dx.doi.org/10.1126/sciadv.abp8075
work_keys_str_mv AT xiangli anepidermalelectronicsystemforphysiologicalinformationacquisitionprocessingandstoragewithanintegratedflashmemoryarray
AT wangyuru anepidermalelectronicsystemforphysiologicalinformationacquisitionprocessingandstoragewithanintegratedflashmemoryarray
AT xiafan anepidermalelectronicsystemforphysiologicalinformationacquisitionprocessingandstoragewithanintegratedflashmemoryarray
AT liufang anepidermalelectronicsystemforphysiologicalinformationacquisitionprocessingandstoragewithanintegratedflashmemoryarray
AT hedaliang anepidermalelectronicsystemforphysiologicalinformationacquisitionprocessingandstoragewithanintegratedflashmemoryarray
AT longguanhua anepidermalelectronicsystemforphysiologicalinformationacquisitionprocessingandstoragewithanintegratedflashmemoryarray
AT zengxiangwen anepidermalelectronicsystemforphysiologicalinformationacquisitionprocessingandstoragewithanintegratedflashmemoryarray
AT liangxuelei anepidermalelectronicsystemforphysiologicalinformationacquisitionprocessingandstoragewithanintegratedflashmemoryarray
AT jinchuanhong anepidermalelectronicsystemforphysiologicalinformationacquisitionprocessingandstoragewithanintegratedflashmemoryarray
AT wangyuwei anepidermalelectronicsystemforphysiologicalinformationacquisitionprocessingandstoragewithanintegratedflashmemoryarray
AT pananlian anepidermalelectronicsystemforphysiologicalinformationacquisitionprocessingandstoragewithanintegratedflashmemoryarray
AT penglianmao anepidermalelectronicsystemforphysiologicalinformationacquisitionprocessingandstoragewithanintegratedflashmemoryarray
AT huyoufan anepidermalelectronicsystemforphysiologicalinformationacquisitionprocessingandstoragewithanintegratedflashmemoryarray
AT xiangli epidermalelectronicsystemforphysiologicalinformationacquisitionprocessingandstoragewithanintegratedflashmemoryarray
AT wangyuru epidermalelectronicsystemforphysiologicalinformationacquisitionprocessingandstoragewithanintegratedflashmemoryarray
AT xiafan epidermalelectronicsystemforphysiologicalinformationacquisitionprocessingandstoragewithanintegratedflashmemoryarray
AT liufang epidermalelectronicsystemforphysiologicalinformationacquisitionprocessingandstoragewithanintegratedflashmemoryarray
AT hedaliang epidermalelectronicsystemforphysiologicalinformationacquisitionprocessingandstoragewithanintegratedflashmemoryarray
AT longguanhua epidermalelectronicsystemforphysiologicalinformationacquisitionprocessingandstoragewithanintegratedflashmemoryarray
AT zengxiangwen epidermalelectronicsystemforphysiologicalinformationacquisitionprocessingandstoragewithanintegratedflashmemoryarray
AT liangxuelei epidermalelectronicsystemforphysiologicalinformationacquisitionprocessingandstoragewithanintegratedflashmemoryarray
AT jinchuanhong epidermalelectronicsystemforphysiologicalinformationacquisitionprocessingandstoragewithanintegratedflashmemoryarray
AT wangyuwei epidermalelectronicsystemforphysiologicalinformationacquisitionprocessingandstoragewithanintegratedflashmemoryarray
AT pananlian epidermalelectronicsystemforphysiologicalinformationacquisitionprocessingandstoragewithanintegratedflashmemoryarray
AT penglianmao epidermalelectronicsystemforphysiologicalinformationacquisitionprocessingandstoragewithanintegratedflashmemoryarray
AT huyoufan epidermalelectronicsystemforphysiologicalinformationacquisitionprocessingandstoragewithanintegratedflashmemoryarray