A widespread length-dependent splicing dysregulation in cancer

Dysregulation of alternative splicing is a key molecular hallmark of cancer. However, the common features and underlying mechanisms remain unclear. Here, we report an intriguing length-dependent splicing regulation in cancers. By systematically analyzing the transcriptome of thousands of cancer pati...

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Detalles Bibliográficos
Autores principales: Zhang, Sirui, Mao, Miaowei, Lv, Yuesheng, Yang, Yingqun, He, Weijing, Song, Yongmei, Wang, Yongbo, Yang, Yun, Al Abo, Muthana, Freedman, Jennifer A., Patierno, Steven R., Wang, Yang, Wang, Zefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385142/
https://www.ncbi.nlm.nih.gov/pubmed/35977015
http://dx.doi.org/10.1126/sciadv.abn9232

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