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Regulation of the Signal-Dependent E Protein HEBAlt Through a YYY Motif Is Required for Progression Through T Cell Development
The E protein transcription factors E2A and HEB are critical for many developmental processes, including T cell development. We have shown that the Tcf12 locus gives rise to two distinct HEB proteins, with alternative (HEBAlt) and canonical (HEBCan) N-terminal domains, which are co-expressed during...
Autores principales: | Yoganathan, Kogulan, Yan, Anqi, Rocha, Juliana, Trotman-Grant, Ashton, Mohtashami, Mahmood, Wells, Lisa, Zúñiga-Pflücker, Juan Carlos, Anderson, Michele K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385190/ https://www.ncbi.nlm.nih.gov/pubmed/35990644 http://dx.doi.org/10.3389/fimmu.2022.848577 |
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