Cargando…

Disturbance of Fatty Acid Metabolism Promoted Vascular Endothelial Cell Senescence via Acetyl-CoA-Induced Protein Acetylation Modification

Endothelial cell senescence is the main risk factor contributing to vascular dysfunction and the progression of aging-related cardiovascular diseases. However, the relationship between endothelial cell metabolism and endothelial senescence remains unclear. The present study provides novel insight in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Tong, Yang, Wan-qi, Luo, Wen-wei, Zhang, Li-li, Mai, Yan-qi, Li, Zi-qing, Liu, Si-tong, Jiang, Lu-jing, Liu, Pei-qing, Li, Zhuo-ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385365/ https://www.ncbi.nlm.nih.gov/pubmed/35993026 http://dx.doi.org/10.1155/2022/1198607

Ejemplares similares

Acetyl-CoA Carboxylases and Diseases
por: Wang, Yu, et al.
Publicado: (2022)

ACETYL-COA SYNTHETASE REGULATES HISTONE ACETYLATION AND HIPPOCAMPAL MEMORY
por: Mews, Philipp, et al.
Publicado: (2017)

Acetyl-CoA flux regulates the proteome and acetyl-proteome to maintain intracellular metabolic crosstalk
por: Dieterich, Inca A., et al.
Publicado: (2019)

Acetylation Modification During Autophagy and Vascular Aging
por: Sun, Jiaxing, et al.
Publicado: (2021)

Acetyl-CoA derived from hepatic mitochondrial fatty acid β-oxidation aggravates inflammation by enhancing p65 acetylation
por: Chen, Qiang, et al.
Publicado: (2021)

Acetylation-mediated remodeling of the nucleolus regulates cellular acetyl-CoA responses
por: Houston, Ryan, et al.
Publicado: (2020)

Acetyl-CoA Metabolism and Histone Acetylation in the Regulation of Aging and Lifespan
por: Bradshaw, Patrick C.
Publicado: (2021)

Chemical Genetics of Acetyl-CoA Carboxylases
por: Zu, Xuyu, et al.
Publicado: (2013)

Activation of acetyl-CoA synthetase 2 mediates kidney injury in diabetic nephropathy
por: Lu, Jian, et al.
Publicado: (2023)

TIGAR promotes neural stem cell differentiation through acetyl-CoA-mediated histone acetylation
por: Zhou, Wenjuan, et al.
Publicado: (2019)

Soybean Oil Regulates the Fatty Acid Synthesis II System of Bacillus amyloliquefaciens LFB112 by Activating Acetyl-CoA Levels
por: Cheng, Qiang, et al.
Publicado: (2023)

Intracellular Citrate/acetyl-CoA flux and endoplasmic reticulum acetylation: Connectivity is the answer
por: Fernandez-Fuente, Gonzalo, et al.
Publicado: (2022)

The mitochondrion of Plasmodium falciparum is required for cellular acetyl-CoA metabolism and protein acetylation
por: Nair, Sethu C., et al.
Publicado: (2023)

Modulation of plant acetyl-CoA synthetase activity by post-translational lysine acetylation
por: Sofeo, Naazneen, et al.
Publicado: (2023)

N-terminal Acetylation Levels Are Maintained During Acetyl-CoA Deficiency in Saccharomyces cerevisiae
por: Varland, Sylvia, et al.
Publicado: (2018)

Mitochondrial acetyl-CoA reversibly regulates locus-specific histone acetylation and gene expression
por: Lozoya, Oswaldo A, et al.
Publicado: (2019)

ApoE4 exacerbates the senescence of hippocampal neurons and spatial cognitive impairment by downregulating acetyl‐CoA level
por: Lv, Shuixin, et al.
Publicado: (2023)

Crystal structure of the 500 kD yeast acetyl-CoA carboxylase holoenzyme dimer
por: Wei, Jia, et al.
Publicado: (2015)

Acetyl-CoA and the Regulation of Metabolism: Mechanisms and Consequences
por: Shi, Lei, et al.
Publicado: (2015)

The dynamic organization of fungal acetyl-CoA carboxylase
por: Hunkeler, Moritz, et al.
Publicado: (2016)

A unified molecular mechanism for the regulation of acetyl-CoA carboxylase by phosphorylation
por: Wei, Jia, et al.
Publicado: (2016)

A unified molecular mechanism for the regulation of acetyl-CoA carboxylase by phosphorylation
por: Wei, Jia, et al.
Publicado: (2017)

Acetyl-CoA production by specific metabolites promotes cardiac repair after myocardial infarction via histone acetylation
por: Lei, Ienglam, et al.
Publicado: (2021)

Modification of Epigenetic Histone Acetylation in Hepatocellular Carcinoma
por: Liu, Kwei-Yan, et al.
Publicado: (2018)

N-acetylaspartate catabolism determines cytosolic acetyl-CoA levels and histone acetylation in brown adipocytes
por: Prokesch, A., et al.
Publicado: (2016)

Carnitine octanoyltransferase is important for the assimilation of exogenous acetyl-L-carnitine into acetyl-CoA in mammalian cells
por: Hsu, Jake, et al.
Publicado: (2022)

Alternative polyadenylation regulates acetyl-CoA carboxylase function in peanut
por: Peng, Zhenying, et al.
Publicado: (2023)

Enzymatic characterization of two acetyl-CoA synthetase genes from Populus trichocarpa
por: Cao, Shan, et al.
Publicado: (2016)

Acetyl-CoA metabolism drives epigenome change and contributes to carcinogenesis risk in fatty liver disease
por: Assante, Gabriella, et al.
Publicado: (2022)

Hepatic conversion of acetyl-CoA to acetate plays crucial roles in energy stress
por: Wang, Jinyang, et al.
Publicado: (2023)

Construction of acetyl-CoA and DBAT hybrid metabolic pathway for acetylation of 10-deacetylbaccatin III to baccatin III
por: Wang, Hao, et al.
Publicado: (2021)

Role of Motif III in Catalysis by Acetyl-CoA Synthetase
por: Ingram-Smith, Cheryl, et al.
Publicado: (2012)

Acetyl-CoA-directed gene transcription in cancer cells
por: Martínez-Reyes, Inmaculada, et al.
Publicado: (2018)

Older Than Genes: The Acetyl CoA Pathway and Origins
por: Martin, William F.
Publicado: (2020)

Dynamics of the Degradation of Acetyl-CoA Carboxylase Herbicides in Vegetables
por: Jursík, Miroslav, et al.
Publicado: (2021)

Targeting acetyl-CoA carboxylase 1 for cancer therapy
por: Yu, Yong, et al.
Publicado: (2023)

Gaining access to acetyl-CoA by peroxisomal surface display
por: Perrot, Thomas, et al.
Publicado: (2023)

Acetyl-CoA flux from the cytosol to the ER regulates engagement and quality of the secretory pathway
por: Dieterich, Inca A., et al.
Publicado: (2021)

Increased expression of fatty acid synthase and acetyl-CoA carboxylase in the prefrontal cortex and cerebellum in the valproic acid model of autism
por: Chen, Jianling, et al.
Publicado: (2016)

The role of acetyl-coA carboxylase2 in head and neck squamous cell carcinoma
por: Li, Kun, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_buegsha8vp2lodcf6fcu81eg5p