Growth-promoting function of the cGAS-STING pathway in triple-negative breast cancer cells

The cGAS-STING axis is one of the key mechanisms guarding cells from pathogen invasion in the cytoplasmic compartment. Sensing of foreign DNA in the cytosol by the cGAS-STING axis triggers a stress cascade, culminating at stimulation of the protein kinase TBK1 and subsequently activation of inflamma...

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Detalles Bibliográficos
Autores principales: Liu, Liang-Chih, Shen, Yi-Chun, Wang, Yuan-Liang, Wu, Wan-Rong, Chang, Ling-Chu, Chen, Ya-Huey, Lee, Chuan-Chun, Wang, Shao-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385397/
https://www.ncbi.nlm.nih.gov/pubmed/35992877
http://dx.doi.org/10.3389/fonc.2022.851795

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