Trained immunity of alveolar macrophages requires metabolic rewiring and type 1 interferon signaling

Environmental microbial triggers shape the development and functionality of the immune system. Alveolar macrophages (AMs), tissue-resident macrophages of the lungs, are in constant and direct contact with inhaled particles and microbes. Such exposures likely impact AM reactivity to subsequent challe...

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Detalles Bibliográficos
Autores principales: Zahalka, Sophie, Starkl, Philipp, Watzenboeck, Martin L., Farhat, Asma, Radhouani, Mariem, Deckert, Florian, Hladik, Anastasiya, Lakovits, Karin, Oberndorfer, Felicitas, Lassnig, Caroline, Strobl, Birgit, Klavins, Kristaps, Matsushita, Mai, Sanin, David E., Grzes, Katarzyna M., Pearce, Edward J., Gorki, Anna-Dorothea, Knapp, Sylvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385480/
https://www.ncbi.nlm.nih.gov/pubmed/35856089
http://dx.doi.org/10.1038/s41385-022-00528-5

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