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Attenuation of allodynia and microglial reactivity by inhibiting the degradation of 2-arachidonoylglycerol following injury to the trigeminal nerve in mice

Endocannabinoids have an important role for the regulation of neuropathic pain. In our previous study, we observed that preventing the degradation of a endocannabinoid, 2-arachidonoylglycerol (2-AG), using an inhibitor of monoacylglycerol lipase (JZL184), attenuated neuropathic orofacial pain (NOP)....

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Detalles Bibliográficos
Autores principales:	Kamimura, Rantaro, Hossain, Mohammad Zakir, Takahashi, Kojiro, Saito, Isao, Kitagawa, Junichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385535/ https://www.ncbi.nlm.nih.gov/pubmed/35991988 http://dx.doi.org/10.1016/j.heliyon.2022.e10034

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