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Triptolide Alleviates Oxidized LDL-Induced Endothelial Inflammation by Attenuating the Oxidative Stress-Mediated Nuclear Factor-Kappa B Pathway

BACKGROUND: Endothelial inflammation triggered by oxidized LDL (ox-LDL) is a crucial mechanism involved in atherosclerosis. Triptolide (TP), a primary active ingredient of the traditional Chinese medicine Tripterygium wilfordii Hook F, possesses antioxidant and anti-inflammatory properties in vivo....

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Detalles Bibliográficos
Autores principales: Zhang, Shiyu, Xie, Shiyang, Gao, Yuan, Wang, Youping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385561/
https://www.ncbi.nlm.nih.gov/pubmed/35989981
http://dx.doi.org/10.1016/j.curtheres.2022.100683