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Tissue-specific identification of multi-omics features for pan-cancer drug response prediction
Current statistical models for drug response prediction and biomarker identification fall short in leveraging the shared and unique information from various cancer tissues and multi-omics profiles. We developed mix-lasso model that introduces an additional sample group penalty term to capture tissue...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385562/ https://www.ncbi.nlm.nih.gov/pubmed/35992090 http://dx.doi.org/10.1016/j.isci.2022.104767 |