Structural basis for proton coupled cystine transport by cystinosin

Amino acid transporters play a key role controlling the flow of nutrients across the lysosomal membrane and regulating metabolism in the cell. Mutations in the gene encoding the transporter cystinosin result in cystinosis, an autosomal recessive metabolic disorder characterised by the accumulation o...

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Detalles Bibliográficos
Autores principales: Löbel, Mark, Salphati, Sacha P., El Omari, Kamel, Wagner, Armin, Tucker, Stephen J., Parker, Joanne L., Newstead, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385667/
https://www.ncbi.nlm.nih.gov/pubmed/35977944
http://dx.doi.org/10.1038/s41467-022-32589-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385667/
https://www.ncbi.nlm.nih.gov/pubmed/35977944
http://dx.doi.org/10.1038/s41467-022-32589-2

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