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A protocol to use Drosophila melanogaster larvae to model human glioblastoma

This protocol describes a genetic model system we developed for glioblastoma (GBM) in Drosophila melanogaster, which can be used to explore the pathogenic phenotypic effects of mutated genetic pathways and to identify potential therapeutic targets for tumors with these mutations. We present genetic...

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Detalles Bibliográficos
Autores principales: Saborio, Julia G., Young, Elizabeth E., Chen, Alexander S., Read, Renee D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385699/
https://www.ncbi.nlm.nih.gov/pubmed/35990742
http://dx.doi.org/10.1016/j.xpro.2022.101609