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Cryo-EM structures of the channelrhodopsin ChRmine in lipid nanodiscs

Microbial channelrhodopsins are light-gated ion channels widely used for optogenetic manipulation of neuronal activity. ChRmine is a bacteriorhodopsin-like cation channelrhodopsin (BCCR) more closely related to ion pump rhodopsins than other channelrhodopsins. ChRmine displays unique properties favo...

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Detalles Bibliográficos
Autores principales: Tucker, Kyle, Sridharan, Savitha, Adesnik, Hillel, Brohawn, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385719/
https://www.ncbi.nlm.nih.gov/pubmed/35977941
http://dx.doi.org/10.1038/s41467-022-32441-7