Nomograms predicting cancer-specific survival for stage IV colorectal cancer with synchronous lung metastases

This study aimed to establish a nomogram for the prediction of cancer-specific survival (CSS) of CRC patients with synchronous LM. The final prognostic nomogram based on prognostic factors was evaluated by concordance index (C-index), time-dependent receiver operating characteristic curves, and cali...

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Autores principales: Cheng, Pu, Chen, Haipeng, Huang, Fei, Li, Jiyun, Liu, Hengchang, Zheng, Zhaoxu, Lu, Zhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385743/
https://www.ncbi.nlm.nih.gov/pubmed/35977984
http://dx.doi.org/10.1038/s41598-022-18258-w
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author Cheng, Pu
Chen, Haipeng
Huang, Fei
Li, Jiyun
Liu, Hengchang
Zheng, Zhaoxu
Lu, Zhao
author_facet Cheng, Pu
Chen, Haipeng
Huang, Fei
Li, Jiyun
Liu, Hengchang
Zheng, Zhaoxu
Lu, Zhao
author_sort Cheng, Pu
collection PubMed
description This study aimed to establish a nomogram for the prediction of cancer-specific survival (CSS) of CRC patients with synchronous LM. The final prognostic nomogram based on prognostic factors was evaluated by concordance index (C-index), time-dependent receiver operating characteristic curves, and calibration curves. In the training and validation groups, the C-index for the nomogram was 0.648 and 0.638, and the AUC was 0.793 and 0.785, respectively. The high quality of the calibration curves in the nomogram models for CSS at 1-, 3-, and 5-year was observed. The nomogram model provided a conventional and useful tool to evaluate the 1-, 3-, and 5-year CSS of CRC patients with synchronous LM.
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spelling pubmed-93857432022-08-19 Nomograms predicting cancer-specific survival for stage IV colorectal cancer with synchronous lung metastases Cheng, Pu Chen, Haipeng Huang, Fei Li, Jiyun Liu, Hengchang Zheng, Zhaoxu Lu, Zhao Sci Rep Article This study aimed to establish a nomogram for the prediction of cancer-specific survival (CSS) of CRC patients with synchronous LM. The final prognostic nomogram based on prognostic factors was evaluated by concordance index (C-index), time-dependent receiver operating characteristic curves, and calibration curves. In the training and validation groups, the C-index for the nomogram was 0.648 and 0.638, and the AUC was 0.793 and 0.785, respectively. The high quality of the calibration curves in the nomogram models for CSS at 1-, 3-, and 5-year was observed. The nomogram model provided a conventional and useful tool to evaluate the 1-, 3-, and 5-year CSS of CRC patients with synchronous LM. Nature Publishing Group UK 2022-08-17 /pmc/articles/PMC9385743/ /pubmed/35977984 http://dx.doi.org/10.1038/s41598-022-18258-w Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Cheng, Pu
Chen, Haipeng
Huang, Fei
Li, Jiyun
Liu, Hengchang
Zheng, Zhaoxu
Lu, Zhao
Nomograms predicting cancer-specific survival for stage IV colorectal cancer with synchronous lung metastases
title Nomograms predicting cancer-specific survival for stage IV colorectal cancer with synchronous lung metastases
title_full Nomograms predicting cancer-specific survival for stage IV colorectal cancer with synchronous lung metastases
title_fullStr Nomograms predicting cancer-specific survival for stage IV colorectal cancer with synchronous lung metastases
title_full_unstemmed Nomograms predicting cancer-specific survival for stage IV colorectal cancer with synchronous lung metastases
title_short Nomograms predicting cancer-specific survival for stage IV colorectal cancer with synchronous lung metastases
title_sort nomograms predicting cancer-specific survival for stage iv colorectal cancer with synchronous lung metastases
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385743/
https://www.ncbi.nlm.nih.gov/pubmed/35977984
http://dx.doi.org/10.1038/s41598-022-18258-w
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