Double-stranded RNA induction asa potential dynamic biomarkerfor DNA-demethylating agents

Hypomethylating agents (HMAs), such as azacitidine and decitabine, induce cancer cell death by demethylating DNAs to promote the expression of tumor-suppressor genes. HMAs also reactivate the transcription of endogenous double-stranded RNAs (dsRNAs) that trigger the innate immune response and subseq...

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Detalles Bibliográficos
Autores principales: Kang, Minjeong, Kharbash, Raisa, Byun, Ja Min, Jeon, Jaemin, Ali, Ahsan Ausaf, Ku, Doyeong, Yoon, Jimin, Ku, Yongsuk, Sohn, Jooyeon, Lee, Seung-Jae V., Shin, Dong-Yeop, Koh, Youngil, Yoon, Sung-Soo, Hong, Junshik, Kim, Yoosik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385881/
https://www.ncbi.nlm.nih.gov/pubmed/36035755
http://dx.doi.org/10.1016/j.omtn.2022.07.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385881/
https://www.ncbi.nlm.nih.gov/pubmed/36035755
http://dx.doi.org/10.1016/j.omtn.2022.07.014

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