Cargando…

Novel Designed Proteolytically Resistant VEGF-B186R127S Promotes Angiogenesis in Mouse Heart by Recruiting Endothelial Progenitor Cells

Background: Previous studies have indicated that vascular endothelial growth factor B186 (VEGF-B186) supports coronary vascular growth in normal and ischemic myocardium. However, previous studies also indicated that induction of ventricular arrhythmias is a severe side effect preventing the use of V...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mallick, Rahul, Gurzeler, Erika, Toivanen, Pyry I., Nieminen, Tiina, Ylä-Herttuala, Seppo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9385986/ https://www.ncbi.nlm.nih.gov/pubmed/35992336 http://dx.doi.org/10.3389/fbioe.2022.907538

Ejemplares similares

Adenoviral VEGF-B186R127S gene transfer induces angiogenesis and improves perfusion in ischemic heart
por: Korpela, Henna, et al.
Publicado: (2021)

Snake venom VEGF Vammin induces a highly efficient angiogenic response in skeletal muscle via VEGFR-2/NRP specific signaling
por: Toivanen, Pyry I., et al.
Publicado: (2017)

Axon Guidance-Related Factor FLRT3 Regulates VEGF-Signaling and Endothelial Cell Function
por: Jauhiainen, Suvi, et al.
Publicado: (2019)

Therapeutic Potential of VEGF-B in Coronary Heart Disease and Heart Failure: Dream or Vision?
por: Mallick, Rahul, et al.
Publicado: (2022)

Long Non-Coding RNA Modulation of VEGF-A during Hypoxia
por: Nieminen, Tiina, et al.
Publicado: (2018)

Doxycycline modulates VEGF-A expression: Failure of doxycycline-inducible lentivirus shRNA vector to knockdown VEGF-A expression in transgenic mice
por: Merentie, Mari, et al.
Publicado: (2018)

Adenoviral VEGF-D(ΔN ΔC) gene therapy for myocardial ischemia
por: Pajula, Juho, et al.
Publicado: (2022)

Left ventricular remodeling leads to heart failure in mice with cardiac‐specific overexpression of VEGF‐B(167): echocardiography and magnetic resonance imaging study
por: Lottonen‐Raikaslehto, Line, et al.
Publicado: (2017)

AAV2-VEGF-B gene therapy failed to induce angiogenesis in ischemic porcine myocardium due to inflammatory responses
por: Korpela, Henna, et al.
Publicado: (2022)

Editorial: Vascularization for Regenerative Medicine
por: Banfi, Andrea, et al.
Publicado: (2018)

Epigenetic Regulation of Vascular Smooth Muscle Cell Phenotype Switching in Atherosclerotic Artery Remodeling: A Mini-Review
por: Zurek, Michelle, et al.
Publicado: (2021)

Adenoviral intramyocardial VEGF-D(ΔNΔC) gene transfer increases myocardial perfusion reserve in refractory angina patients: a phase I/IIa study with 1-year follow-up
por: Hartikainen, Juha, et al.
Publicado: (2017)

SUR1-E1506K mutation impairs glucose tolerance and promotes vulnerable atherosclerotic plaque phenotype in hypercholesterolemic mice
por: Gurzeler, Erika, et al.
Publicado: (2021)

EphrinB2/EphB4 signaling regulates non‐sprouting angiogenesis by VEGF
por: Groppa, Elena, et al.
Publicado: (2018)

Optimized riboswitch-regulated AAV vector for VEGF-B gene therapy
por: Eriksson, Reetta A. E., et al.
Publicado: (2022)

A 96-well format for a high-throughput baculovirus generation, fast titering and recombinant protein production in insect and mammalian cells
por: Kärkkäinen, Hanna-Riikka, et al.
Publicado: (2009)

Corrigendum: Optimized riboswitch-regulated AAV vector for VEGF-B gene therapy
por: Eriksson, Reetta A. E., et al.
Publicado: (2023)

Expression profiles of VEGF-A, VEGF-D and VEGFR1 are higher in distant metastases than in matched primary high grade epithelial ovarian cancer
por: Sopo, Minna, et al.
Publicado: (2019)

BMP6/TAZ-Hippo signaling modulates angiogenesis and endothelial cell response to VEGF
por: Pulkkinen, H. H., et al.
Publicado: (2020)

Non-proteolytic calpain-6 interacts with VEGFA and promotes angiogenesis by increasing VEGF secretion
por: Oh, Mijung, et al.
Publicado: (2019)

Vascular Endothelial Growth Factor-B Induces a Distinct Electrophysiological Phenotype in Mouse Heart
por: Naumenko, Nikolay, et al.
Publicado: (2017)

Gene Therapy Used in Cancer Treatment
por: Wirth, Thomas, et al.
Publicado: (2014)

Characterization of a functional endothelial super-enhancer that regulates ADAMTS18 and angiogenesis
por: Mushimiyimana, Isidore, et al.
Publicado: (2021)

Gamma-Secretase Inhibitor Treatment Promotes VEGF-A-Driven Blood Vessel Growth and Vascular Leakage but Disrupts Neovascular Perfusion
por: Kalén, Mattias, et al.
Publicado: (2011)

Lymphatic insufficiency leads to distinct myocardial infarct content assessed by magnetic resonance T(RAFFn), T(1ρ) and T(2) relaxation times
por: Ylä-Herttuala, Elias, et al.
Publicado: (2023)

Sustained Release of VEGF to Promote Angiogenesis and Osteointegration of Three-Dimensional Printed Biomimetic Titanium Alloy Implants
por: Li, Youbin, et al.
Publicado: (2021)

Control of VEGF-A transcriptional programs by pausing and genomic compartmentalization
por: Kaikkonen, Minna U., et al.
Publicado: (2014)

Downregulation of VEGFR3 signaling alters cardiac lymphatic vessel organization and leads to a higher mortality after acute myocardial infarction
por: Vuorio, Taina, et al.
Publicado: (2018)

Long-term safety and efficacy of intramyocardial adenovirus-mediated VEGF-D(ΔNΔC) gene therapy eight-year follow-up of phase I KAT301 study
por: Leikas, Aleksi J., et al.
Publicado: (2021)

Promoting blood vessel growth in ischemic diseases: challenges in translating preclinical potential into clinical success
por: Dragneva, Galina, et al.
Publicado: (2013)

Dotted collar placed around carotid artery induces asymmetric neointimal lesion formation in rabbits without intravascular manipulations
por: Kivelä, Antti, et al.
Publicado: (2012)

Characterization of a new IN-I-PpoI fusion protein and a homology-arm containing transgene cassette that improve transgene expression persistence and 28S rRNA gene-targeted insertion of lentiviral vectors
por: Nousiainen, Alisa, et al.
Publicado: (2023)

Robust Angiogenesis and Arteriogenesis in the Skin of Diabetic Mice by Transient Delivery of Engineered VEGF and PDGF-BB Proteins in Fibrin Hydrogels
por: Certelli, Alessandro, et al.
Publicado: (2021)

VEGF-Loaded Heparinised Gelatine-Hydroxyapatite-Tricalcium Phosphate Scaffold Accelerates Bone Regeneration via Enhancing Osteogenesis-Angiogenesis Coupling
por: Chen, Xu, et al.
Publicado: (2022)

In vivo inhibition of nuclear factor of activated T-cells leads to atherosclerotic plaque regression in IGF-II/LDLR(–/–)ApoB(100/100) mice
por: Blanco, Fabiana, et al.
Publicado: (2018)

A New Gene Therapy Approach for Cardiovascular Disease by Non-coding RNAs Acting in the Nucleus
por: Husso, Tiia, et al.
Publicado: (2014)

Nucleic Acid–Based Therapies for Atherosclerosis
por: Mäkinen, Petri, et al.
Publicado: (2020)

Novel RNAi-Based Therapies for Atherosclerosis
por: Ruotsalainen, Anna-Kaisa, et al.
Publicado: (2021)

A multipurpose vector system for the screening of libraries in bacteria, insect and mammalian cells and expression in vivo
por: Laitinen, Olli H., et al.
Publicado: (2005)

Pluronic F127-Modified Electrospun Fibrous Meshes for Synergistic Combination Chemotherapy of Colon Cancer
por: Xie, Dengchao, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_jlknskmfs38mcvgqjc6i9l8rja