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Treatment with β-blocker nebivolol ameliorates oxidative stress and endothelial dysfunction in tenofovir-induced nephrotoxicity in rats

BACKGROUND: Tenofovir disoproxil fumarate (TDF), a widely prescribed component in antiretroviral regimens, has been associated with nephrotoxicity. Nebivolol is a third generation selective β-1 adrenergic receptor blocker and may protect renal structure and function through the suppression of oxidat...

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Detalles Bibliográficos
Autores principales: Nascimento, Mariana Moura, Bernardo, Desiree Rita Denelle, de Bragança, Ana Carolina, Massola Shimizu, Maria Heloisa, Seguro, Antonio Carlos, Volpini, Rildo Aparecido, Canale, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386005/
https://www.ncbi.nlm.nih.gov/pubmed/35991671
http://dx.doi.org/10.3389/fmed.2022.953749