Multiomics characterization implicates PTK7 in ovarian cancer EMT and cell plasticity and offers strategies for therapeutic intervention

Most patients with ovarian cancer (OC) are diagnosed at a late stage when there are very few therapeutic options and a poor prognosis. This is due to the lack of clearly defined underlying mechanisms or an oncogenic addiction that can be targeted pharmacologically, unlike other types of cancer. Here...

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Detalles Bibliográficos
Autores principales: Raivola, Juuli, Dini, Alice, Karvonen, Hanna, Piki, Emilia, Salokas, Kari, Niininen, Wilhelmiina, Kaleva, Laura, Zhang, Kaiyang, Arjama, Mariliina, Gudoityte, Greta, Seashore-Ludlow, Brinton, Varjosalo, Markku, Kallioniemi, Olli, Hautaniemi, Sampsa, Murumägi, Astrid, Ungureanu, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386025/
https://www.ncbi.nlm.nih.gov/pubmed/35977930
http://dx.doi.org/10.1038/s41419-022-05161-5

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