Identification of a drug-response gene in multiple myeloma through longitudinal single-cell transcriptome sequencing

Despite recent therapeutic advances for multiple myeloma (MM), relapse is very common. Here, we conducted longitudinal single-cell transcriptome sequencing (scRNA-seq) of MM cells from a patient with relapsed MM, treated with multiple anti-myeloma drugs. We observed five subclusters of MM cells, whi...

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Detalles Bibliográficos
Autores principales: Masuda, Toru, Haji, Shojiro, Nakashima, Yasuhiro, Tsuda, Mariko, Kimura, Daisaku, Takamatsu, Akiko, Iwahashi, Norifusa, Umakoshi, Hironobu, Shiratsuchi, Motoaki, Kikutake, Chie, Suyama, Mikita, Ohkawa, Yasuyuki, Ogawa, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386061/
https://www.ncbi.nlm.nih.gov/pubmed/35992084
http://dx.doi.org/10.1016/j.isci.2022.104781

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