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A Joint Model Considering Measurement Errors for Optimally Identifying Tumor Mutation Burden Threshold

Tumor mutation burden (TMB) is a recognized stratification biomarker for immunotherapy. Nevertheless, the general TMB-high threshold is unstandardized due to severe clinical controversies, with the underlying cause being inconsistency between multiple assessment criteria and imprecision of the TMB v...

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Detalles Bibliográficos
Autores principales:	Wang, Yixuan, Lai, Xin, Wang, Jiayin, Xu, Ying, Zhang, Xuanping, Zhu, Xiaoyan, Liu, Yuqian, Shao, Yang, Zhang, Li, Fang, Wenfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386083/ https://www.ncbi.nlm.nih.gov/pubmed/35991549 http://dx.doi.org/10.3389/fgene.2022.915839

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