Unfolding the genotype-to-phenotype black box of cardiovascular diseases through cross-scale modeling

Complex traits such as cardiovascular diseases (CVD) are the results of complicated processes jointly affected by genetic and environmental factors. Genome-wide association studies (GWAS) identified genetic variants associated with diseases but usually did not reveal the underlying mechanisms. There...

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Detalles Bibliográficos
Autores principales: Xi, Xi, Li, Haochen, Chen, Shengquan, Lv, Tingting, Ma, Tianxing, Jiang, Rui, Zhang, Ping, Wong, Wing Hung, Zhang, Xuegong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386115/
https://www.ncbi.nlm.nih.gov/pubmed/35992073
http://dx.doi.org/10.1016/j.isci.2022.104790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386115/
https://www.ncbi.nlm.nih.gov/pubmed/35992073
http://dx.doi.org/10.1016/j.isci.2022.104790

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