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Unfolding the genotype-to-phenotype black box of cardiovascular diseases through cross-scale modeling
Complex traits such as cardiovascular diseases (CVD) are the results of complicated processes jointly affected by genetic and environmental factors. Genome-wide association studies (GWAS) identified genetic variants associated with diseases but usually did not reveal the underlying mechanisms. There...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386115/ https://www.ncbi.nlm.nih.gov/pubmed/35992073 http://dx.doi.org/10.1016/j.isci.2022.104790 |