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Association between phase angle and coronary artery calcium score in patients on peritoneal dialysis

INTRODUCTION: The phase angle (PhA) has been used as a nutritional marker and predictor of mortality in patients on peritoneal dialysis (PD). The coronary artery calcium (CAC) score has shown to predict the incidence of acute myocardial infarction and death from cardiovascular disease in these patie...

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Detalles Bibliográficos
Autores principales: Reis, Fabricio Moreira, da Silva, Maryanne Zilli Canedo, Reis, Nayrana Soares do Carmo, Costa, Fabiana Lourenço, da Silveira, Caroline Ferreira da Silva Mazeto Pupo, Barretti, Pasqual, Martin, Luis Cuadrado, Bazan, Silméia Garcia Zanati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386310/
https://www.ncbi.nlm.nih.gov/pubmed/35990362
http://dx.doi.org/10.3389/fnut.2022.912642
Descripción
Sumario:INTRODUCTION: The phase angle (PhA) has been used as a nutritional marker and predictor of mortality in patients on peritoneal dialysis (PD). The coronary artery calcium (CAC) score has shown to predict the incidence of acute myocardial infarction and death from cardiovascular disease in these patients. However, the association between PhA and CAC score in patients with PD is not well-established, which is the objective of this study. MATERIALS AND METHODS: Cross-sectional study with patients on PD, followed up at a University Hospital, between March 2018 and August 2019. PhA was evaluated by unifrequency bioimpedance (BIA). The CAC score was calculated based on cardiovascular computed tomography, considering positive when greater than or equal to 100 Agatston and negative when less than 100 Agatston. RESULTS: We evaluated 44 patients on dialysis, with a mean age of 56 years and median time on dialysis therapy was 11.7 months. In the statistical analysis, a significant association was only observed between the CAC score and the PhA. CONCLUSION: The PhA is associated with a positive CAC score in patients with PD, and despite other factors, may be useful as a risk marker for coronary artery disease in this population.