Forskolin-induced organoid swelling is associated with long-term cystic fibrosis disease progression

RATIONALE: Cystic fibrosis (CF) is a monogenic life-shortening disease associated with highly variable individual disease progression which is difficult to predict. Here we assessed the association of forskolin-induced swelling (FIS) of patient-derived organoids with long-term CF disease progression...

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Detalles Bibliográficos
Autores principales: Muilwijk, Danya, de Poel, Eyleen, van Mourik, Peter, Suen, Sylvia W.F., Vonk, Annelotte M., Brunsveld, Jesse E., Kruisselbrink, Evelien, Oppelaar, Hugo, Hagemeijer, Marne C., Berkers, Gitte, de Winter-de Groot, Karin M., Heida-Michel, Sabine, Jans, Stephan R., van Panhuis, Hannah, van der Eerden, Menno M., van der Meer, Renske, Roukema, Jolt, Dompeling, Edward, Weersink, Els J.M., Koppelman, Gerard H., Vries, Robert, Zomer-van Ommen, Domenique D., Eijkemans, Marinus J.C., van der Ent, Cornelis K., Beekman, Jeffrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2022
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386333/
https://www.ncbi.nlm.nih.gov/pubmed/35086832
http://dx.doi.org/10.1183/13993003.00508-2021

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