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Tuberculous Dactylitis in a Case of Multiple Scrofuloderma
This paper reports a case of tuberculous dactylitis and multiple scrofuloderma spreading through the lymph nodes. Scrofuloderma, also known as tuberculosis colliquativa cutis, is a form of cutaneous tuberculosis (TB) that occurs most often in children and young adults and involves the skin over the...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386432/ https://www.ncbi.nlm.nih.gov/pubmed/36158861 http://dx.doi.org/10.1159/000525464 |
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author | Menaldi, Sri Linuwih S.W. Lubis, Farah Faulin Fadhilla, Jhauharina Rizki Widaty, Sandra |
author_facet | Menaldi, Sri Linuwih S.W. Lubis, Farah Faulin Fadhilla, Jhauharina Rizki Widaty, Sandra |
author_sort | Menaldi, Sri Linuwih S.W. |
collection | PubMed |
description | This paper reports a case of tuberculous dactylitis and multiple scrofuloderma spreading through the lymph nodes. Scrofuloderma, also known as tuberculosis colliquativa cutis, is a form of cutaneous tuberculosis (TB) that occurs most often in children and young adults and involves the skin over the infection focus (i.e., lymph nodes, bones, or joints). Scrofuloderma can affect the lower limbs and upper arms by spreading osteomyelitis TB on the humerus, wrist, and elbow. This study reports the case of a 19-year-old man who initially developed painful and swollen skin, followed by the appearance of numerous recurring lumps on the left arm and hand and the right foot, as well as the folding right hamstring, over 3 years. The patient had no clinical improvement with antibiotics and excision. Radiography of the left hand showed tuberculous dactylitis. A biopsy of the left arm was performed, and Ziehl-Neelsen staining showed acid-fast bacilli. Mycobacterium tuberculosis was confirmed by a real-time polymerase chain reaction. Anti-TB drug treatment was initiated with rifampicin, isoniazid, pyrazinamide, and ethambutol, and debridement was performed on the left hand, which resulted in significant improvement of the lesion. Atypical clinical manifestations and unawareness of M. tuberculosis as an underlying disease delayed the diagnosis and treatment of this patient with tuberculous dactylitis and multiple scrofuloderma. |
format | Online Article Text |
id | pubmed-9386432 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-93864322022-09-23 Tuberculous Dactylitis in a Case of Multiple Scrofuloderma Menaldi, Sri Linuwih S.W. Lubis, Farah Faulin Fadhilla, Jhauharina Rizki Widaty, Sandra Case Rep Dermatol Single Case This paper reports a case of tuberculous dactylitis and multiple scrofuloderma spreading through the lymph nodes. Scrofuloderma, also known as tuberculosis colliquativa cutis, is a form of cutaneous tuberculosis (TB) that occurs most often in children and young adults and involves the skin over the infection focus (i.e., lymph nodes, bones, or joints). Scrofuloderma can affect the lower limbs and upper arms by spreading osteomyelitis TB on the humerus, wrist, and elbow. This study reports the case of a 19-year-old man who initially developed painful and swollen skin, followed by the appearance of numerous recurring lumps on the left arm and hand and the right foot, as well as the folding right hamstring, over 3 years. The patient had no clinical improvement with antibiotics and excision. Radiography of the left hand showed tuberculous dactylitis. A biopsy of the left arm was performed, and Ziehl-Neelsen staining showed acid-fast bacilli. Mycobacterium tuberculosis was confirmed by a real-time polymerase chain reaction. Anti-TB drug treatment was initiated with rifampicin, isoniazid, pyrazinamide, and ethambutol, and debridement was performed on the left hand, which resulted in significant improvement of the lesion. Atypical clinical manifestations and unawareness of M. tuberculosis as an underlying disease delayed the diagnosis and treatment of this patient with tuberculous dactylitis and multiple scrofuloderma. S. Karger AG 2022-07-08 /pmc/articles/PMC9386432/ /pubmed/36158861 http://dx.doi.org/10.1159/000525464 Text en Copyright © 2022 by The Author(s). Published by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission. |
spellingShingle | Single Case Menaldi, Sri Linuwih S.W. Lubis, Farah Faulin Fadhilla, Jhauharina Rizki Widaty, Sandra Tuberculous Dactylitis in a Case of Multiple Scrofuloderma |
title | Tuberculous Dactylitis in a Case of Multiple Scrofuloderma |
title_full | Tuberculous Dactylitis in a Case of Multiple Scrofuloderma |
title_fullStr | Tuberculous Dactylitis in a Case of Multiple Scrofuloderma |
title_full_unstemmed | Tuberculous Dactylitis in a Case of Multiple Scrofuloderma |
title_short | Tuberculous Dactylitis in a Case of Multiple Scrofuloderma |
title_sort | tuberculous dactylitis in a case of multiple scrofuloderma |
topic | Single Case |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386432/ https://www.ncbi.nlm.nih.gov/pubmed/36158861 http://dx.doi.org/10.1159/000525464 |
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