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Tuberculous Dactylitis in a Case of Multiple Scrofuloderma

This paper reports a case of tuberculous dactylitis and multiple scrofuloderma spreading through the lymph nodes. Scrofuloderma, also known as tuberculosis colliquativa cutis, is a form of cutaneous tuberculosis (TB) that occurs most often in children and young adults and involves the skin over the...

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Autores principales: Menaldi, Sri Linuwih S.W., Lubis, Farah Faulin, Fadhilla, Jhauharina Rizki, Widaty, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386432/
https://www.ncbi.nlm.nih.gov/pubmed/36158861
http://dx.doi.org/10.1159/000525464
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author Menaldi, Sri Linuwih S.W.
Lubis, Farah Faulin
Fadhilla, Jhauharina Rizki
Widaty, Sandra
author_facet Menaldi, Sri Linuwih S.W.
Lubis, Farah Faulin
Fadhilla, Jhauharina Rizki
Widaty, Sandra
author_sort Menaldi, Sri Linuwih S.W.
collection PubMed
description This paper reports a case of tuberculous dactylitis and multiple scrofuloderma spreading through the lymph nodes. Scrofuloderma, also known as tuberculosis colliquativa cutis, is a form of cutaneous tuberculosis (TB) that occurs most often in children and young adults and involves the skin over the infection focus (i.e., lymph nodes, bones, or joints). Scrofuloderma can affect the lower limbs and upper arms by spreading osteomyelitis TB on the humerus, wrist, and elbow. This study reports the case of a 19-year-old man who initially developed painful and swollen skin, followed by the appearance of numerous recurring lumps on the left arm and hand and the right foot, as well as the folding right hamstring, over 3 years. The patient had no clinical improvement with antibiotics and excision. Radiography of the left hand showed tuberculous dactylitis. A biopsy of the left arm was performed, and Ziehl-Neelsen staining showed acid-fast bacilli. Mycobacterium tuberculosis was confirmed by a real-time polymerase chain reaction. Anti-TB drug treatment was initiated with rifampicin, isoniazid, pyrazinamide, and ethambutol, and debridement was performed on the left hand, which resulted in significant improvement of the lesion. Atypical clinical manifestations and unawareness of M. tuberculosis as an underlying disease delayed the diagnosis and treatment of this patient with tuberculous dactylitis and multiple scrofuloderma.
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spelling pubmed-93864322022-09-23 Tuberculous Dactylitis in a Case of Multiple Scrofuloderma Menaldi, Sri Linuwih S.W. Lubis, Farah Faulin Fadhilla, Jhauharina Rizki Widaty, Sandra Case Rep Dermatol Single Case This paper reports a case of tuberculous dactylitis and multiple scrofuloderma spreading through the lymph nodes. Scrofuloderma, also known as tuberculosis colliquativa cutis, is a form of cutaneous tuberculosis (TB) that occurs most often in children and young adults and involves the skin over the infection focus (i.e., lymph nodes, bones, or joints). Scrofuloderma can affect the lower limbs and upper arms by spreading osteomyelitis TB on the humerus, wrist, and elbow. This study reports the case of a 19-year-old man who initially developed painful and swollen skin, followed by the appearance of numerous recurring lumps on the left arm and hand and the right foot, as well as the folding right hamstring, over 3 years. The patient had no clinical improvement with antibiotics and excision. Radiography of the left hand showed tuberculous dactylitis. A biopsy of the left arm was performed, and Ziehl-Neelsen staining showed acid-fast bacilli. Mycobacterium tuberculosis was confirmed by a real-time polymerase chain reaction. Anti-TB drug treatment was initiated with rifampicin, isoniazid, pyrazinamide, and ethambutol, and debridement was performed on the left hand, which resulted in significant improvement of the lesion. Atypical clinical manifestations and unawareness of M. tuberculosis as an underlying disease delayed the diagnosis and treatment of this patient with tuberculous dactylitis and multiple scrofuloderma. S. Karger AG 2022-07-08 /pmc/articles/PMC9386432/ /pubmed/36158861 http://dx.doi.org/10.1159/000525464 Text en Copyright © 2022 by The Author(s). Published by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Single Case
Menaldi, Sri Linuwih S.W.
Lubis, Farah Faulin
Fadhilla, Jhauharina Rizki
Widaty, Sandra
Tuberculous Dactylitis in a Case of Multiple Scrofuloderma
title Tuberculous Dactylitis in a Case of Multiple Scrofuloderma
title_full Tuberculous Dactylitis in a Case of Multiple Scrofuloderma
title_fullStr Tuberculous Dactylitis in a Case of Multiple Scrofuloderma
title_full_unstemmed Tuberculous Dactylitis in a Case of Multiple Scrofuloderma
title_short Tuberculous Dactylitis in a Case of Multiple Scrofuloderma
title_sort tuberculous dactylitis in a case of multiple scrofuloderma
topic Single Case
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386432/
https://www.ncbi.nlm.nih.gov/pubmed/36158861
http://dx.doi.org/10.1159/000525464
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