Disrupting the plastidic iron-sulfur cluster biogenesis pathway in Toxoplasma gondii has pleiotropic effects irreversibly impacting parasite viability

Like many other apicomplexan parasites, Toxoplasma gondii contains a plastid harboring key metabolic pathways, including the sulfur utilization factor (SUF) pathway that is involved in the biosynthesis of iron-sulfur clusters. These cofactors are crucial for a variety of proteins involved in importa...

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Detalles Bibliográficos
Autores principales: Renaud, Eléa A., Pamukcu, Sarah, Cerutti, Aude, Berry, Laurence, Lemaire-Vieille, Catherine, Yamaryo-Botté, Yoshiki, Botté, Cyrille Y., Besteiro, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386495/
https://www.ncbi.nlm.nih.gov/pubmed/35810787
http://dx.doi.org/10.1016/j.jbc.2022.102243

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