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SARS-CoV-2 breakthrough infection in vaccinees induces virus-specific nasal-resident CD8(+) and CD4(+) T cells of broad specificity

Rapid recognition of SARS-CoV-2–infected cells by resident T cells in the upper airway might provide an important layer of protection against COVID-19. Whether parenteral SARS-CoV-2 vaccination or infection induces nasal-resident T cells specific for distinct SARS-CoV-2 proteins is unknown. We isola...

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Detalles Bibliográficos
Autores principales: Lim, Joey Ming Er, Tan, Anthony Tanoto, Le Bert, Nina, Hang, Shou Kit, Low, Jenny Guek Hong, Bertoletti, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386509/
https://www.ncbi.nlm.nih.gov/pubmed/35972472
http://dx.doi.org/10.1084/jem.20220780