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Ultrarare Coding Variants and Cognitive Function in Schizophrenia

IMPORTANCE: Impaired cognitive function in schizophrenia is associated with poor functional outcomes, but the role of rare coding variants is unclear. OBJECTIVE: To determine whether ultrarare constrained variants (URCVs) are associated with cognition in patients with schizophrenia. DESIGN, SETTING,...

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Detalles Bibliográficos
Autores principales:	Creeth, Hugo D. J., Rees, Elliott, Legge, Sophie E., Dennison, Charlotte A., Holmans, Peter, Walters, James T. R., O’Donovan, Michael C., Owen, Michael J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Medical Association 2022
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386603/ https://www.ncbi.nlm.nih.gov/pubmed/35976659 http://dx.doi.org/10.1001/jamapsychiatry.2022.2289

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