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(68)Ga-Labeled Maleimide for Blood Pool and Lymph PET Imaging through Covalent Bonding to Serum Albumin In Vivo

[Image: see text] This study aims to develop a novel (68)Ga-labeled tracer, which can covalently bind to albumin in vivo based on the maleimide–thiol strategy, and to evaluate its potential applications using positron emission tomography (PET). (68)Ga-labeled maleimide-monoamide-DOTA (denoted as [(6...

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Detalles Bibliográficos
Autores principales: Feng, Lixia, Fang, Jianyang, Zeng, Xinying, Liu, Huanhuan, Zhang, Jingru, Huang, Lumei, Guo, Zhide, Zhuang, Rongqiang, Zhang, Xianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386703/
https://www.ncbi.nlm.nih.gov/pubmed/35990434
http://dx.doi.org/10.1021/acsomega.2c03505