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Augmentation of NAD(+) by Dunnione Ameliorates Imiquimod-Induced Psoriasis-Like Dermatitis in Mice
BACKGROUND: Dunnione has anti-inflammatory properties arising from its ability to alter the ratio of NAD(+)/NADH through NAD(P)H quinone oxidoreductase 1 (NQO1) enzymatic action, followed by subsequent inhibition of NF-κB and inflammatory cytokines. Psoriasis is a chronic, inflammatory skin disorder...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386739/ https://www.ncbi.nlm.nih.gov/pubmed/35991005 http://dx.doi.org/10.2147/JIR.S372543 |