Autocitrullination and Changes in the Activity of Peptidylarginine Deiminase 3 Induced by High Ca(2+) Concentrations

[Image: see text] Peptidylarginine deiminases (PADs) are enzymes that catalyze the Ca(2+)-dependent conversion of arginine residues into proteins to citrulline residues. Five PAD isozymes have been identified in mammals. Several studies have shown that the active-site pockets of these isozymes are f...

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Autores principales: Sawata, Mizuki, Shima, Hiroki, Murayama, Kazutaka, Matsui, Toshitaka, Igarashi, Kazuhiko, Funabashi, Kazumasa, Ite, Kenji, Kizawa, Kenji, Takahara, Hidenari, Unno, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386831/
https://www.ncbi.nlm.nih.gov/pubmed/35990454
http://dx.doi.org/10.1021/acsomega.2c02972

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