Low-cost and clinically applicable copy number profiling using repeat DNA

BACKGROUND: Somatic copy number alterations (SCNAs) are an important class of genomic alteration in cancer. They are frequently observed in cancer samples, with studies showing that, on average, SCNAs affect 34% of a cancer cell’s genome. Furthermore, SCNAs have been shown to be major drivers of tum...

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Detalles Bibliográficos
Autores principales: Abujudeh, Sam, Zeki, Sebastian S., van Lanschot, Meta C.J., Pusung, Mark, Weaver, Jamie M.J., Li, Xiaodun, Noorani, Ayesha, Metz, Andrew J., Bornschein, Jan, Bower, Lawrence, Miremadi, Ahmad, Fitzgerald, Rebecca C., Morrissey, Edward R., Lynch, Andy G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386984/
https://www.ncbi.nlm.nih.gov/pubmed/35978291
http://dx.doi.org/10.1186/s12864-022-08681-8

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