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Breathing and tilting: mesoscale simulations illuminate influenza glycoprotein vulnerabilities

Influenza virus has resurfaced recently from inactivity during the early stages of the COVID-19 pandemic, raising serious concerns about the nature and magnitude of future epidemics. The main antigenic targets of influenza virus are two surface glycoproteins, hemagglutinin (HA) and neuraminidase (NA...

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Detalles Bibliográficos
Autores principales: Casalino, Lorenzo, Seitz, Christian, Lederhofer, Julia, Tsybovsky, Yaroslav, Wilson, Ian A., Kanekiyo, Masaru, Amaro, Rommie E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387122/
https://www.ncbi.nlm.nih.gov/pubmed/35982676
http://dx.doi.org/10.1101/2022.08.02.502576