NF-κB inhibitor alpha has a cross-variant role during SARS-CoV-2 infection in ACE2-overexpressing human airway organoids

As SARS-CoV-2 continues to spread worldwide, tractable primary airway cell models that accurately recapitulate the cell-intrinsic response to arising viral variants are needed. Here we describe an adult stem cell-derived human airway organoid model overexpressing the ACE2 receptor that supports robu...

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Detalles Bibliográficos
Autores principales: Simoneau, Camille R., Chen, Pei-Yi, Xing, Galen K., Khalid, Mir M., Meyers, Nathan L., Hayashi, Jennifer M., Taha, Taha Y., Leon, Kristoffer E., Ashuach, Tal, Fontaine, Krystal A., Rodriguez, Lauren, Joehnk, Bastian, Walcott, Keith, Vasudevan, Sreelakshmi, Fang, Xiaohui, Maishan, Mazharul, Schultz, Shawn, Roose, Jeroen, Matthay, Michael A., Sil, Anita, Arjomandi, Mehrdad, Yosef, Nir, Ott, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387123/
https://www.ncbi.nlm.nih.gov/pubmed/35982664
http://dx.doi.org/10.1101/2022.08.02.502100

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