Compendium of proteins containing segments that exhibit zero‐tolerance to amino acid variation in humans

Genetic missense tolerance ratio (MTR) analysis systematically evaluates all possible segments in a given protein‐encoding transcript found in the human population. This method scores each segment for the number of observed missense variants versus the number of silent mutations in that same segment...

Descripción completa

Detalles Bibliográficos
Autores principales: Sanders, Adam L., Hermanson, Jake N., Samuels, David C., Plate, Lars, Sanders, Charles R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Full‐length Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387208/
https://www.ncbi.nlm.nih.gov/pubmed/36040257
http://dx.doi.org/10.1002/pro.4408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387208/
https://www.ncbi.nlm.nih.gov/pubmed/36040257
http://dx.doi.org/10.1002/pro.4408

Ejemplares similares