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Compendium of proteins containing segments that exhibit zero‐tolerance to amino acid variation in humans
Genetic missense tolerance ratio (MTR) analysis systematically evaluates all possible segments in a given protein‐encoding transcript found in the human population. This method scores each segment for the number of observed missense variants versus the number of silent mutations in that same segment...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons, Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387208/ https://www.ncbi.nlm.nih.gov/pubmed/36040257 http://dx.doi.org/10.1002/pro.4408 |