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Tauroursodeoxycholic Acid Inhibits Clostridioides difficile Toxin-Induced Apoptosis
C. difficile infection (CDI) is a highly inflammatory disease mediated by the production of two large toxins that weaken the intestinal epithelium and cause extensive colonic tissue damage. Antibiotic alternative therapies for CDI are urgently needed as current antibiotic regimens prolong the pertur...
Autores principales: | Pike, Colleen M., Tam, John, Melnyk, Roman A., Theriot, Casey M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387233/ https://www.ncbi.nlm.nih.gov/pubmed/35862710 http://dx.doi.org/10.1128/iai.00153-22 |
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