Surface-tailoring of emulsomes for boosting brain delivery of vinpocetine via intranasal route: in vitro optimization and in vivo pharmacokinetic assessment

Vinpocetine (VNP), a semisynthetic active pharmaceutical ingredient, is used for oral management of cerebrovascular diseases because of its ability to enhance the blood flow to the brain. However, despite that, the therapeutic application of VNP is restricted due to its reduced bioavailability and d...

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Detalles Bibliográficos
Autores principales: Aldawsari, Hibah M., Badr-Eldin, Shaimaa M., Assiri, Nourah Y., Alhakamy, Nabil A., Privitera, Anna, Caraci, Filippo, Caruso, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387308/
https://www.ncbi.nlm.nih.gov/pubmed/35975309
http://dx.doi.org/10.1080/10717544.2022.2110996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387308/
https://www.ncbi.nlm.nih.gov/pubmed/35975309
http://dx.doi.org/10.1080/10717544.2022.2110996

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