SARS‐CoV‐2 triggers complement activation through interactions with heparan sulfate

OBJECTIVES: To determine whether SARS‐CoV‐2 can trigger complement activation, the pathways that are involved and the functional significance of the resultant effect. METHODS: SARS‐CoV‐2 was inoculated into a human lepirudin‐anticoagulated whole blood model, which contains a full repertoire of compl...

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Detalles Bibliográficos
Autores principales: Lo, Martin W, Amarilla, Alberto A, Lee, John D, Albornoz, Eduardo A, Modhiran, Naphak, Clark, Richard J, Ferro, Vito, Chhabra, Mohit, Khromykh, Alexander A, Watterson, Daniel, Woodruff, Trent M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387400/
https://www.ncbi.nlm.nih.gov/pubmed/35999893
http://dx.doi.org/10.1002/cti2.1413

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