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Future research directions to identify risks and mitigation strategies for neurostructural, ocular, and behavioral changes induced by human spaceflight: A NASA-ESA expert group consensus report

A team of experts on the effects of the spaceflight environment on the brain and eye (SANS: Spaceflight-Associated Neuro-ocular Syndrome) was convened by NASA and ESA to (1) review spaceflight-associated structural and functional changes of the human brain and eye, and any interactions between the t...

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Autores principales: Seidler, Rachael D., Stern, Claudia, Basner, Mathias, Stahn, Alexander C., Wuyts, Floris L., zu Eulenburg, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387435/
https://www.ncbi.nlm.nih.gov/pubmed/35991346
http://dx.doi.org/10.3389/fncir.2022.876789
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author Seidler, Rachael D.
Stern, Claudia
Basner, Mathias
Stahn, Alexander C.
Wuyts, Floris L.
zu Eulenburg, Peter
author_facet Seidler, Rachael D.
Stern, Claudia
Basner, Mathias
Stahn, Alexander C.
Wuyts, Floris L.
zu Eulenburg, Peter
author_sort Seidler, Rachael D.
collection PubMed
description A team of experts on the effects of the spaceflight environment on the brain and eye (SANS: Spaceflight-Associated Neuro-ocular Syndrome) was convened by NASA and ESA to (1) review spaceflight-associated structural and functional changes of the human brain and eye, and any interactions between the two; and (2) identify critical future research directions in this area to help characterize the risk and identify possible countermeasures and strategies to mitigate the spaceflight-induced brain and eye alterations. The experts identified 14 critical future research directions that would substantially advance our knowledge of the effects of spending prolonged periods of time in the spaceflight environment on SANS, as well as brain structure and function. They used a paired comparison approach to rank the relative importance of these 14 recommendations, which are discussed in detail in the main report and are summarized briefly below.
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spelling pubmed-93874352022-08-19 Future research directions to identify risks and mitigation strategies for neurostructural, ocular, and behavioral changes induced by human spaceflight: A NASA-ESA expert group consensus report Seidler, Rachael D. Stern, Claudia Basner, Mathias Stahn, Alexander C. Wuyts, Floris L. zu Eulenburg, Peter Front Neural Circuits Neural Circuits A team of experts on the effects of the spaceflight environment on the brain and eye (SANS: Spaceflight-Associated Neuro-ocular Syndrome) was convened by NASA and ESA to (1) review spaceflight-associated structural and functional changes of the human brain and eye, and any interactions between the two; and (2) identify critical future research directions in this area to help characterize the risk and identify possible countermeasures and strategies to mitigate the spaceflight-induced brain and eye alterations. The experts identified 14 critical future research directions that would substantially advance our knowledge of the effects of spending prolonged periods of time in the spaceflight environment on SANS, as well as brain structure and function. They used a paired comparison approach to rank the relative importance of these 14 recommendations, which are discussed in detail in the main report and are summarized briefly below. Frontiers Media S.A. 2022-08-04 /pmc/articles/PMC9387435/ /pubmed/35991346 http://dx.doi.org/10.3389/fncir.2022.876789 Text en Copyright © 2022 Seidler, Stern, Basner, Stahn, Wuyts and zu Eulenburg. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neural Circuits
Seidler, Rachael D.
Stern, Claudia
Basner, Mathias
Stahn, Alexander C.
Wuyts, Floris L.
zu Eulenburg, Peter
Future research directions to identify risks and mitigation strategies for neurostructural, ocular, and behavioral changes induced by human spaceflight: A NASA-ESA expert group consensus report
title Future research directions to identify risks and mitigation strategies for neurostructural, ocular, and behavioral changes induced by human spaceflight: A NASA-ESA expert group consensus report
title_full Future research directions to identify risks and mitigation strategies for neurostructural, ocular, and behavioral changes induced by human spaceflight: A NASA-ESA expert group consensus report
title_fullStr Future research directions to identify risks and mitigation strategies for neurostructural, ocular, and behavioral changes induced by human spaceflight: A NASA-ESA expert group consensus report
title_full_unstemmed Future research directions to identify risks and mitigation strategies for neurostructural, ocular, and behavioral changes induced by human spaceflight: A NASA-ESA expert group consensus report
title_short Future research directions to identify risks and mitigation strategies for neurostructural, ocular, and behavioral changes induced by human spaceflight: A NASA-ESA expert group consensus report
title_sort future research directions to identify risks and mitigation strategies for neurostructural, ocular, and behavioral changes induced by human spaceflight: a nasa-esa expert group consensus report
topic Neural Circuits
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387435/
https://www.ncbi.nlm.nih.gov/pubmed/35991346
http://dx.doi.org/10.3389/fncir.2022.876789
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