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Knowledge of Hepatitis C virus vertical transmission and subsequent pregnancy outcome in virus-positive female blood donors

INTRODUCTION: Hepatitis C virus (HCV) can be vertically transmitted from mother to fetus. We evaluated knowledge about HCV vertical transmission in female blood donors who became pregnant following detection of HCV in their donated blood. METHODS: This was a retrospective descriptive study of female...

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Autores principales: Ranes de Menezes Filho, Hélio, Maia, Ludmila Grego, Machado, Soraia Mafra, Ramos da Silva, Iasmin, de Almeida-Neto, Cesar, Sabino, Ester Cerdeira, Witkin, Steven S., Mendes-Corrêa, Maria Cássia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387468/
https://www.ncbi.nlm.nih.gov/pubmed/35180448
http://dx.doi.org/10.1016/j.bjid.2022.102334
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author Ranes de Menezes Filho, Hélio
Maia, Ludmila Grego
Machado, Soraia Mafra
Ramos da Silva, Iasmin
de Almeida-Neto, Cesar
Sabino, Ester Cerdeira
Witkin, Steven S.
Mendes-Corrêa, Maria Cássia
author_facet Ranes de Menezes Filho, Hélio
Maia, Ludmila Grego
Machado, Soraia Mafra
Ramos da Silva, Iasmin
de Almeida-Neto, Cesar
Sabino, Ester Cerdeira
Witkin, Steven S.
Mendes-Corrêa, Maria Cássia
author_sort Ranes de Menezes Filho, Hélio
collection PubMed
description INTRODUCTION: Hepatitis C virus (HCV) can be vertically transmitted from mother to fetus. We evaluated knowledge about HCV vertical transmission in female blood donors who became pregnant following detection of HCV in their donated blood. METHODS: This was a retrospective descriptive study of females seen at a single blood bank in Sao Paulo, Brazil who were diagnosed with HCV infection in their donated blood. HCV-infected donors who subsequently became pregnant were invited to participate through letters or phone calls. Individuals who agreed to participate were interviewed by questionnaire to evaluate their knowledge on HCV vertical transmission. RESULTS: Among 282 HCV-positive female blood donors, 69 reported becoming pregnant after their HCV diagnosis in donated blood. While 24 of these women were successful treated for their infection prior to becoming pregnant, 45 (65.2%) were at risk for vertical HCV transmission either because they had never been treated for HCV, were pregnant before treatment or became pregnant after unsuccessful treatment. Of the 59 women who responded to the question of whether they were informed about the risk of HCV vertical transmission, 58 (98.3%) reported never receiving this information either after obtaining their blood donation results or during their pregnancy. CONCLUSION: The lack of knowledge of HCV-infected women on the possibility for mother-to-child transmission of this virus highlights the critical need to improve communication about pregnancy-related risks between health professionals and HCV-infected women of childbearing age.
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spelling pubmed-93874682022-08-23 Knowledge of Hepatitis C virus vertical transmission and subsequent pregnancy outcome in virus-positive female blood donors Ranes de Menezes Filho, Hélio Maia, Ludmila Grego Machado, Soraia Mafra Ramos da Silva, Iasmin de Almeida-Neto, Cesar Sabino, Ester Cerdeira Witkin, Steven S. Mendes-Corrêa, Maria Cássia Braz J Infect Dis Original Article INTRODUCTION: Hepatitis C virus (HCV) can be vertically transmitted from mother to fetus. We evaluated knowledge about HCV vertical transmission in female blood donors who became pregnant following detection of HCV in their donated blood. METHODS: This was a retrospective descriptive study of females seen at a single blood bank in Sao Paulo, Brazil who were diagnosed with HCV infection in their donated blood. HCV-infected donors who subsequently became pregnant were invited to participate through letters or phone calls. Individuals who agreed to participate were interviewed by questionnaire to evaluate their knowledge on HCV vertical transmission. RESULTS: Among 282 HCV-positive female blood donors, 69 reported becoming pregnant after their HCV diagnosis in donated blood. While 24 of these women were successful treated for their infection prior to becoming pregnant, 45 (65.2%) were at risk for vertical HCV transmission either because they had never been treated for HCV, were pregnant before treatment or became pregnant after unsuccessful treatment. Of the 59 women who responded to the question of whether they were informed about the risk of HCV vertical transmission, 58 (98.3%) reported never receiving this information either after obtaining their blood donation results or during their pregnancy. CONCLUSION: The lack of knowledge of HCV-infected women on the possibility for mother-to-child transmission of this virus highlights the critical need to improve communication about pregnancy-related risks between health professionals and HCV-infected women of childbearing age. Elsevier 2022-02-16 /pmc/articles/PMC9387468/ /pubmed/35180448 http://dx.doi.org/10.1016/j.bjid.2022.102334 Text en © 2022 Sociedade Brasileira de Infectologia. Published by Elsevier España, S.L.U. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Original Article
Ranes de Menezes Filho, Hélio
Maia, Ludmila Grego
Machado, Soraia Mafra
Ramos da Silva, Iasmin
de Almeida-Neto, Cesar
Sabino, Ester Cerdeira
Witkin, Steven S.
Mendes-Corrêa, Maria Cássia
Knowledge of Hepatitis C virus vertical transmission and subsequent pregnancy outcome in virus-positive female blood donors
title Knowledge of Hepatitis C virus vertical transmission and subsequent pregnancy outcome in virus-positive female blood donors
title_full Knowledge of Hepatitis C virus vertical transmission and subsequent pregnancy outcome in virus-positive female blood donors
title_fullStr Knowledge of Hepatitis C virus vertical transmission and subsequent pregnancy outcome in virus-positive female blood donors
title_full_unstemmed Knowledge of Hepatitis C virus vertical transmission and subsequent pregnancy outcome in virus-positive female blood donors
title_short Knowledge of Hepatitis C virus vertical transmission and subsequent pregnancy outcome in virus-positive female blood donors
title_sort knowledge of hepatitis c virus vertical transmission and subsequent pregnancy outcome in virus-positive female blood donors
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387468/
https://www.ncbi.nlm.nih.gov/pubmed/35180448
http://dx.doi.org/10.1016/j.bjid.2022.102334
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