A Randomized Trial of Lipid Metabolism Modulation with Fenofibrate for Acute Coronavirus Disease 2019

BACKGROUND: Abnormal cellular lipid metabolism appears to underlie SARS-CoV-2 cytotoxicity and may involve inhibition of peroxisome proliferator activated receptor alpha (PPARα). Fenofibrate, a PPAR-α activator, modulates cellular lipid metabolism. Fenofibric acid has also been shown to affect the d...

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Detalles Bibliográficos
Autores principales: Chirinos, Julio, Lopez-Jaramillo, Patricio, Giamarellos-Bourboulis, Evangelos, Dávila-del-Carpio, Gonzalo, Bizri, Abdul, Andrade-Villanueva, Jaime, Salman, Oday, Cure-Cure, Carlos, Rosado-Santander, Nelson, Giraldo, Mario Cornejo, González-Hernández, Luz, Moghnieh, Rima, Angeliki, Rapti, Saldarriaga, María Cruz, Pariona, Marcos, Medina, Carola, Dimitroulis, Ioannis, Vlachopoulos, Charalambos, Gutierrez, Corina, Rodriguez-Mori, Juan, Gomez-Laiton, Edgar, Pereyra, Rosa, Hernández, Jorge Ravelo, Arbañil, Hugo, Accini-Mendoza, José, Pérez-Mayorga, Maritza, Milionis, Haralampos, Poulakou, Garyfallia, Sánchez, Gregorio, Valdivia-Vega, Renzo, Villavicencio-Carranza, Mirko, Ayala-Garcia, Ricardo, Castro-Callirgos, Carlos, Carrasco, Rosa Alfaro, Danos, Willy Lecca, Sharkoski, Tiffany, Greene, Katherine, Pourmussa, Bianca, Greczylo, Candy, Chittams, Jesse, Katsaounou, Paraskevi, Alexiou, Zoi, Sympardi, Styliani, Sweitzer, Nancy, Putt, Mary, Cohen, Jordana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387540/
https://www.ncbi.nlm.nih.gov/pubmed/35982675
http://dx.doi.org/10.21203/rs.3.rs-1933913/v1

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