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Cinematic rendering in rheumatic diseases—Photorealistic depiction of pathologies improves disease understanding for patients
BACKGROUND: Patient education is crucial for successful chronic disease management. Current education material for rheumatic patients however rarely includes images of disease pathologies, limiting patients’ disease understanding. Cinematic rendering (CR) is a new tool that allows segmentation of st...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387553/ https://www.ncbi.nlm.nih.gov/pubmed/35991672 http://dx.doi.org/10.3389/fmed.2022.946106 |
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author | Pachowsky, Milena L. Morf, Harriet Simon, David Schönau, Verena Valor-Mendez, Larissa Knitza, Johannes Fagni, Filippo Engel, Klaus Uder, Michael Hueber, Axel Schmidkonz, Christian Schett, Georg Kleyer, Arnd |
author_facet | Pachowsky, Milena L. Morf, Harriet Simon, David Schönau, Verena Valor-Mendez, Larissa Knitza, Johannes Fagni, Filippo Engel, Klaus Uder, Michael Hueber, Axel Schmidkonz, Christian Schett, Georg Kleyer, Arnd |
author_sort | Pachowsky, Milena L. |
collection | PubMed |
description | BACKGROUND: Patient education is crucial for successful chronic disease management. Current education material for rheumatic patients however rarely includes images of disease pathologies, limiting patients’ disease understanding. Cinematic rendering (CR) is a new tool that allows segmentation of standard medical images (DICOMs) into pictures that illustrate disease pathologies in a photorealistic way. Thus CR has the potential to simplify and improve the explanation of disease pathologies, disease activity and disease consequences and could therefore be a valuable tool to effectively educate and inform patients about their rheumatic and musculoskeletal disease (RMD). OBJECTIVES: To examine the feasibility of creating photorealistic images using CR from RMD patients depicting typical rheumatic disease pathologies and, in a second step to investigate the patient-perceived educational potential of these photorealistic images in clinical routine. METHODS: We selected conventional, high-resolution (HR) and positron emission tomography (PET) computed tomography (CT) images of patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA), axial spondyloarthritis (axSpA), and giant cell arteritis (GCA) that showed typical respective disease pathologies. These images were segmented using CR technique. In a prospective study, physicians used CR-enhanced and conventional original images to explain the depicted pathognomonic pathologies to patients with the respective rheumatic disease. Patients were then asked to complete a questionnaire evaluating the perceived usefulness of being presented with CR-enhanced images to better understand their underlying disease. RESULTS: CR images were successfully generated from above mentioned CT methods. Pathologies such as bone erosions, bony spurs, bone loss, ankylosis, and PET-based inflammation could be visualized in photorealistic detail. A total of 79 patients (61% females) with rheumatic diseases (RA 29%, PsA 29%, axSpA 24%, GCA 18%) were interviewed and answered the quantitative questionnaire. Mean age was 55.4 ± 12.6 years. Irrespective of disease, all patients agreed or highly agreed that CR-based images help to improve disease understanding, should be shown at disease onset, provide a rationale to regularly take medication and would like to have access to their own CR-enhanced images. CONCLUSION: Conventional disease images can successfully be turned into photorealistic disease depictions using CR. Patients perceived CR images as a valuable addition to current patient education, enabling personalized disease education and potentially increased medication adherence. |
format | Online Article Text |
id | pubmed-9387553 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-93875532022-08-19 Cinematic rendering in rheumatic diseases—Photorealistic depiction of pathologies improves disease understanding for patients Pachowsky, Milena L. Morf, Harriet Simon, David Schönau, Verena Valor-Mendez, Larissa Knitza, Johannes Fagni, Filippo Engel, Klaus Uder, Michael Hueber, Axel Schmidkonz, Christian Schett, Georg Kleyer, Arnd Front Med (Lausanne) Medicine BACKGROUND: Patient education is crucial for successful chronic disease management. Current education material for rheumatic patients however rarely includes images of disease pathologies, limiting patients’ disease understanding. Cinematic rendering (CR) is a new tool that allows segmentation of standard medical images (DICOMs) into pictures that illustrate disease pathologies in a photorealistic way. Thus CR has the potential to simplify and improve the explanation of disease pathologies, disease activity and disease consequences and could therefore be a valuable tool to effectively educate and inform patients about their rheumatic and musculoskeletal disease (RMD). OBJECTIVES: To examine the feasibility of creating photorealistic images using CR from RMD patients depicting typical rheumatic disease pathologies and, in a second step to investigate the patient-perceived educational potential of these photorealistic images in clinical routine. METHODS: We selected conventional, high-resolution (HR) and positron emission tomography (PET) computed tomography (CT) images of patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA), axial spondyloarthritis (axSpA), and giant cell arteritis (GCA) that showed typical respective disease pathologies. These images were segmented using CR technique. In a prospective study, physicians used CR-enhanced and conventional original images to explain the depicted pathognomonic pathologies to patients with the respective rheumatic disease. Patients were then asked to complete a questionnaire evaluating the perceived usefulness of being presented with CR-enhanced images to better understand their underlying disease. RESULTS: CR images were successfully generated from above mentioned CT methods. Pathologies such as bone erosions, bony spurs, bone loss, ankylosis, and PET-based inflammation could be visualized in photorealistic detail. A total of 79 patients (61% females) with rheumatic diseases (RA 29%, PsA 29%, axSpA 24%, GCA 18%) were interviewed and answered the quantitative questionnaire. Mean age was 55.4 ± 12.6 years. Irrespective of disease, all patients agreed or highly agreed that CR-based images help to improve disease understanding, should be shown at disease onset, provide a rationale to regularly take medication and would like to have access to their own CR-enhanced images. CONCLUSION: Conventional disease images can successfully be turned into photorealistic disease depictions using CR. Patients perceived CR images as a valuable addition to current patient education, enabling personalized disease education and potentially increased medication adherence. Frontiers Media S.A. 2022-08-03 /pmc/articles/PMC9387553/ /pubmed/35991672 http://dx.doi.org/10.3389/fmed.2022.946106 Text en Copyright © 2022 Pachowsky, Morf, Simon, Schönau, Valor-Mendez, Knitza, Fagni, Engel, Uder, Hueber, Schmidkonz, Schett and Kleyer. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Medicine Pachowsky, Milena L. Morf, Harriet Simon, David Schönau, Verena Valor-Mendez, Larissa Knitza, Johannes Fagni, Filippo Engel, Klaus Uder, Michael Hueber, Axel Schmidkonz, Christian Schett, Georg Kleyer, Arnd Cinematic rendering in rheumatic diseases—Photorealistic depiction of pathologies improves disease understanding for patients |
title | Cinematic rendering in rheumatic diseases—Photorealistic depiction of pathologies improves disease understanding for patients |
title_full | Cinematic rendering in rheumatic diseases—Photorealistic depiction of pathologies improves disease understanding for patients |
title_fullStr | Cinematic rendering in rheumatic diseases—Photorealistic depiction of pathologies improves disease understanding for patients |
title_full_unstemmed | Cinematic rendering in rheumatic diseases—Photorealistic depiction of pathologies improves disease understanding for patients |
title_short | Cinematic rendering in rheumatic diseases—Photorealistic depiction of pathologies improves disease understanding for patients |
title_sort | cinematic rendering in rheumatic diseases—photorealistic depiction of pathologies improves disease understanding for patients |
topic | Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387553/ https://www.ncbi.nlm.nih.gov/pubmed/35991672 http://dx.doi.org/10.3389/fmed.2022.946106 |
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