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TXNIP inhibition in the treatment of diabetes. Verapamil as a novel therapeutic modality in diabetic patients

Loss of pancreatic β–cell is a critical factor in the pathogenesis of type 1 diabetes and it also occurs in type 2. TXNIP (thioredoxin – interacting protein), also known as vitamin D3-upregulated protein 1, or thioredoxin-binding-protein-2, regulates this process and modulates cellular redox balance...

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Detalles Bibliográficos
Autores principales: Borowiec, Agnieszka Magdalena, Właszczuk, Adam, Olakowska, Edyta, Lewin-Kowalik, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iuliu Hatieganu University of Medicine and Pharmacy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387585/
https://www.ncbi.nlm.nih.gov/pubmed/36060506
http://dx.doi.org/10.15386/mpr-2187