Outcomes Following the Use of Angiotensin II in Patients with Postoperative Vasoplegic Syndrome: A Case Series

Catecholamine-resistant postoperative vasoplegic syndrome (PVS) lacks effective treatment modalities. Synthetic angiotensin II was recently approved for the treatment of vasodilatory shock; however, its use in PVS is not well described. We report outcomes in six patients receiving angiotensin II for...

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Autores principales: Konkol, Samuel B., Morrisette, Matthew J., Hulse, Matthew C., Enfield, Kyle B., Mihalek, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387627/
https://www.ncbi.nlm.nih.gov/pubmed/35799569
http://dx.doi.org/10.4103/aca.aca_98_21
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author Konkol, Samuel B.
Morrisette, Matthew J.
Hulse, Matthew C.
Enfield, Kyle B.
Mihalek, Andrew D.
author_facet Konkol, Samuel B.
Morrisette, Matthew J.
Hulse, Matthew C.
Enfield, Kyle B.
Mihalek, Andrew D.
author_sort Konkol, Samuel B.
collection PubMed
description Catecholamine-resistant postoperative vasoplegic syndrome (PVS) lacks effective treatment modalities. Synthetic angiotensin II was recently approved for the treatment of vasodilatory shock; however, its use in PVS is not well described. We report outcomes in six patients receiving angiotensin II for the treatment of isolated PVS. All patients achieved their MAP goal and the majority showed improvement in lactate and background catecholamine dose; however, variables of perfusion changed discordantly. Three of six patients survived to hospital discharge.
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spelling pubmed-93876272022-08-19 Outcomes Following the Use of Angiotensin II in Patients with Postoperative Vasoplegic Syndrome: A Case Series Konkol, Samuel B. Morrisette, Matthew J. Hulse, Matthew C. Enfield, Kyle B. Mihalek, Andrew D. Ann Card Anaesth Case Report Catecholamine-resistant postoperative vasoplegic syndrome (PVS) lacks effective treatment modalities. Synthetic angiotensin II was recently approved for the treatment of vasodilatory shock; however, its use in PVS is not well described. We report outcomes in six patients receiving angiotensin II for the treatment of isolated PVS. All patients achieved their MAP goal and the majority showed improvement in lactate and background catecholamine dose; however, variables of perfusion changed discordantly. Three of six patients survived to hospital discharge. Wolters Kluwer - Medknow 2022 2022-07-05 /pmc/articles/PMC9387627/ /pubmed/35799569 http://dx.doi.org/10.4103/aca.aca_98_21 Text en Copyright: © 2022 Annals of Cardiac Anaesthesia https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Konkol, Samuel B.
Morrisette, Matthew J.
Hulse, Matthew C.
Enfield, Kyle B.
Mihalek, Andrew D.
Outcomes Following the Use of Angiotensin II in Patients with Postoperative Vasoplegic Syndrome: A Case Series
title Outcomes Following the Use of Angiotensin II in Patients with Postoperative Vasoplegic Syndrome: A Case Series
title_full Outcomes Following the Use of Angiotensin II in Patients with Postoperative Vasoplegic Syndrome: A Case Series
title_fullStr Outcomes Following the Use of Angiotensin II in Patients with Postoperative Vasoplegic Syndrome: A Case Series
title_full_unstemmed Outcomes Following the Use of Angiotensin II in Patients with Postoperative Vasoplegic Syndrome: A Case Series
title_short Outcomes Following the Use of Angiotensin II in Patients with Postoperative Vasoplegic Syndrome: A Case Series
title_sort outcomes following the use of angiotensin ii in patients with postoperative vasoplegic syndrome: a case series
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387627/
https://www.ncbi.nlm.nih.gov/pubmed/35799569
http://dx.doi.org/10.4103/aca.aca_98_21
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