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Telescoping bimodal latent Dirichlet allocation to identify expression QTLs across tissues

Expression quantitative trait loci (eQTLs), or single-nucleotide polymorphisms that affect average gene expression levels, provide important insights into context-specific gene regulation. Classic eQTL analyses use one-to-one association tests, which test gene–variant pairs individually and ignore c...

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Detalles Bibliográficos
Autores principales:	Gewirtz, Ariel DH, Townes, F William, Engelhardt, Barbara E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9387650/ https://www.ncbi.nlm.nih.gov/pubmed/35977827 http://dx.doi.org/10.26508/lsa.202101297

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