Biosynthesis of tetrahydropapaverine and semisynthesis of papaverine in yeast

Tetrahydropapaverine (THP) and papaverine are plant natural products with clinically significant roles. THP is a precursor in the production of the drugs atracurium and cisatracurium, and papaverine is used as an antispasmodic during vascular surgery. In recent years, metabolic engineering advances...

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Detalles Bibliográficos
Autores principales: Jamil, Osman K., Cravens, Aaron, Payne, James T., Kim, Colin Y., Smolke, Christina D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388072/
https://www.ncbi.nlm.nih.gov/pubmed/35939674
http://dx.doi.org/10.1073/pnas.2205848119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388072/
https://www.ncbi.nlm.nih.gov/pubmed/35939674
http://dx.doi.org/10.1073/pnas.2205848119

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