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Assignment of structural transitions during mechanical unwrapping of nucleosomes and their disassembly products

Nucleosome DNA unwrapping and its disassembly into hexasomes and tetrasomes is necessary for genomic access and plays an important role in transcription regulation. Previous single-molecule mechanical nucleosome unwrapping revealed a low- and a high-force transitions, and force-FRET pulling experime...

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Detalles Bibliográficos
Autores principales: Díaz-Celis, César, Cañari-Chumpitaz, Cristhian, Sosa, Robert P., Castillo, Juan P., Zhang, Meng, Cheng, Enze, Chen, Andy Q., Vien, Michael, Kim, JeongHoon, Onoa, Bibiana, Bustamante, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9388122/
https://www.ncbi.nlm.nih.gov/pubmed/35939666
http://dx.doi.org/10.1073/pnas.2206513119